Current Results
Science and engineering begin with counting. Health is no different. During this past year, I’ve had hundreds of measurements taken. Some are standard, such as biofluids and fitness scores. Some are advanced, such as MRI and ultrasound. And some uncommon, such as my lungs, nerves, hearing, and intestinal tract. Below is a sampling of these measurements.
Results: Optimal Clinical Outcome Range
| BIOMARKER | RESULT | AGE EQUIVALENT | OPTIMAL CLINICAL OUTCOMES RANGE (OCOR) | |
| ALT | OPTIMAL | 18 | <15 | |
| BMI | OPTIMAL | 22.8 | <22.5 | |
| Fasting plasma glucose | OPTIMAL | 82 | 28 (max reduction) | <95 |
| Body Fat | OPTIMAL | 6.9 | 16 (max reduction) | <10% |
| Cholesterol (total) | OPTIMAL | 158 | ||
| DHEA | OPTIMAL | 149 | 25 (max reduction) | < age 50 |
| Free Testosterone Index | OPTIMAL | 0.39 | 41 | < age 50 |
| GGT | OPTIMAL | 13 | <14 | |
| Glutathione | OPTIMAL | 227 | 29 | < age 30 |
| Grip Strength Dominant | OPTIMAL | 134 | 33 (max reduction) | < age 30 |
| Grip Strength Non-dominant | OPTIMAL | 124 | 43 (max reduction) | < age 30 |
| HbA1C | OPTIMAL | 4.5 | 28 (max reduction) | 4.5-5.6 |
| HDL | OPTIMAL | 73 | 50 - 60 | |
| hsCRP | OPTIMAL | 0.46 | 10 (max reduction) | <0.55 |
| IGF-1 | OPTIMAL | 125 | 75 - 150 | |
| LDL | OPTIMAL | 74 | < 100 | |
| NAD | OPTIMAL | 52.6 | 16 (max reduction) | < age 30 |
| PSA | OPTIMAL | 0.68 | 22 (max reduction) | < age 30 |
| RDW | OPTIMAL | 11.3 | 18 (max reduction) | < age 30 |
| SHBG | OPTIMAL | 68 | ||
| TSH | OPTIMAL | 1.94 | 1 - 2.1 | |
| Triglycerides | OPTIMAL | 55 | 27 - 89 | |
| Testosterone | OPTIMAL | 769 | 33 (max reduction) | |
| VO2 max treadmill | OPTIMAL | 53.6 | 18 (max reduction) | < age 30 |
| WBC | OPTIMAL | 4.5 | 3.5 - 6 | |
| 20th percentile telomeres PBMC | OPTIMAL | 7 | 28 (max reduction) | < age 30 |
Results: Younger than Chronological Age
REJUVENATION POINTS
- hsCRP
- DunedinPoAm
- NAD
- Frailty index
- Total glutathione
- VO2 max
- 12 min run distance
- Whole brain volume
- White matter volume
- Cerebral volume
- Total sleep time
- Wake after sleep onset
- Sleep efficiency
- Digit comparison score
- Digit symbol score
- ETS score
- RAVENS score
- Letter number sequencing score
- Ventricular volumes
- Subcortical grey matter
- Pituitary brightness
- Cerebellar volume
- Stand on 1 leg
- 5 min deep sleep RMSSD
- MaxHR
- BNP
- LVEDV
- LV E
- LV A
- LV E/A
- LV E’m
- LV IVRT
- LV PWT
- LA A’ lat
- LA SRE
- LA SRA
- LA SRE/SRA
- cfPWV
REJUVENATION POINTS
- RCCA PSEM
- LCCA PSEM
- RCCA CIMT
- LCCA CIMT
- RICA CIMT
- LICA CIMT
- TPA
- Systolic blood pressure
- Brachial blood pressure
- Non-map C2 CSBP
- Non-map C2 CDBP
- PPA ratio
- AI
- AP
- FEV1
- FVC
- PEFT
- DLCOc
- A line quant
- MIP
- MEP
- RDW
- EpiTOC2.tnsc
- PC telo length methylation pred
- QFISH median PBMC telo
- QFISH 20th cent PBMC teloRRI left
- RRI right
- Cystatin C
- eGFR CKD EPI
- EHF Hz Right
- 14-16k Hz Left
- Calculus index
- Recession gingival
- Index gingival
- HbA1c
- FPG
- CGM
- Albumin
REJUVENATION POINTS
- QT
- VISIA Tru L
- VISIA Tru R
- ZM-Facial age
- ZM Neck age
- ZM Decollete age
- ZM Gluteal age
- ZM Lower limb age
- Facial left spots
- Facial right spots
- Facial left texture
- Facial right texture
- Facial left brown
- Facial right brown
- Facial left wrinkles
- Facial right wrinkles
- Facial central spots
- Facial central texture
- Facial central browns
- Modified HN hair
- DHEA-S
- Thyroid volumetrics
- Push up continuity
- Bench press 1 rep max
- Leg press 1 rep max
- Grip strength L
- Grip strength R
- WC
- BF%
- DEXA L1-4
- DEXA Femur
- DEXA Hip
- Osteocalcin
- Spinal flexibility
- Prostatic volume
- PSA total
- Total testosterone
- Free testosterone index
IDEAL MARKERS FOR
- Vit A
- Alpha carotene
- Beta Carotene
- Lycopene
- Vit C
- B1
- B2
- B3
- B5
- B6
- B7
- B12
- Vit E (Alpha + Gamma)
- Vit D
- Vit K
- CoQ10
- Bicarbonate
- Calcium
- Chloride
- Chromium
- Copper
- Iodine
- Magnesium
- Phosphate
- Potassium
- Selenium
- Sodium
- Zinc
- ALT
- AST
- ALP
- GGT
- TG
- LDL
- HDL
- IGF-1
Routine Measurement
- Weight, body fat, muscle mass, body water, BMI
- Sleep: HR, HRV, Deep, REM, Respiration Rate, Body Temp
- Waking body temp (ear)
- SpO2 while sleeping
- Blood Glucose
- MRI - whole body
- Ultrasound - whole body
- Biofluids (blood, stool, urine, saliva)
- Physical fitness - whoop + Polar
- VO2Max
- Hearing
- Eyes
- Air quality
Vein health for blood draws (via ultrasound)
- Using ultrasound to evaluate potential vein damage from serial blood draws. No damage found. Bilateral antecubitcal fossae (ACF) venous ultrasound was performed to identify potential venous wall or valve pathology related to serial blood draws of the ACF veins, with no pathology identified, suggesting further draws at this site are safe.
Whole body MRI cancer screening
Nothing suspicious was identified. Head to lower sacral non-contrast 3T T1, T2 and DWI were performed (with some regions missed for DWI), with additional FLAIR on the head region, HASTE on abdominal region and sagittal STIR on C1 to S2 were performed for cancer screening with no suspicious, potentially suspicious or likert ⅗ or greater lesions identified
Sensory nervous system measurements
- Right plantar 2 point discrimination of 1.5 cm coming in at age 30 equivalent
Kidneys
- Zero cysts, zero parenchymal thickness abnormalities (i.e. irregular or thinning) present in the kidneys
- Renal interlobar arteries resistive index (RRI) coming in at 0.46 (right kidney) and 0.49 (left kidney), equal to age 25 of a newly diagnosed essential hypertensive, but otherwise average, western population (ref) (non-hypertensive population data currently not available)
- Thyroid volume (increases with age) coming in at age 23 equivalent at 20.9 milliliters (ref)
Prostate
- Prostate volume (increases with age) coming in at age 30 equivalent for a Westerner at 19.14 milliliters (ref)
New maxHR of 183 bpm, = to age 37, 5% improvement in 90 days. 8% increase (from 169 bpm) in 12 months (originally age 60). 23 year age reduction to date. Exciting because we couldn’t get maxHR to budge for over 12 months. Neither could we find any research showing maxHR increase was possible. Measured w/ Polar H10
Waist circumference measurement 82.8 cm, average for a 25 year old (maximum age reduction)
BIA scale body fat% 21-23 ave BMI, = to age 16 (max reduction)
My Pulse Wave Velocity of 5.7, ranks in 10% <30, top 5% of 45+.
Blood urea nitrogen, a measure of protein intake and kidney function, was lowered to 13 mg/dL, deeper into the optimal range for all cause mortality and scoring age 21 equivalent.
Gene Therapy
Data from my first longevity gene therapy: 160% increase in follistatin levels. Achieving our target objective.
This therapy ranks 7th among lifespan studies, extending mouse lifespan by 30%.
Goals:
. epigenetic age reduction
. monitoring dozen+ organs for possible improvements
. improved muscle volume and strength
. reduced speed of aging
Developed by https://minicircle.io
Heart Health
MEASUREMENT PROTOCOL
- MRI
- Ultrasound
- RHR, HRV, VO2Max
N=1 HIGH ACCURACY METHOD MARKERS
- Resting Heart Rate: 44 bpm
- HRV 54, age 40
- VO2Max 58.7 mL/(kg·min), age 18
- LV septal A’ mitral: age 70+
- Aortic root diameter age 70+
- LA E’ latbasal: age 70+
- RVSP: age 70
- LV sepal E/E’: age 55
- RV E/A: age 52
- MaxHR: age 37
- LV E/A: age 28
[Heart] Carotid arteries
- Pressure strain elastic modulus (PSEM) of the right and left common carotid arteries (RCCA and LCCA) elasticity scoring at 4.51 Pascal units age 26 equivalent and 2.82 Pascal units age 18 equivalent respectively (ref)
- Common carotid average intima media thicknesses age 32 equivalent, at 0.47 mm thickness, although there is little change between age 18 and age 32 (only 0.03 mm) (ref)
- No plaque or atherosclerosis. Details: total plaque area across 6 carotid artery branches of 0 cm^2, showing no significant atherosclerosis; with plaque being defined as any thickening of the intima media beyond 1 mm.
- Internal carotid artery maximum intima media thicknesses age 25 equivalent, as low as is possible to score, at 0.51 and 0.45 mm (ref)
[Heart] Left ventricle
- Intraventricular relaxation time (IVRT) of 50.6 ms scored at age 19 average (ref)
-
E/A pulsed wave doppler in the mitral valve of 1.67 score (dimensionless) coming in at age 28, with the E component at 0.96 m/s of age 15 average for healthy caucasian men (This is a measure of how well blood is flowing through the mitral valve) (ref)
- Tissue doppler showed septal LV E’ (e prime) mitral annulus speed of 11.12 cm/s at age 24 average (ref) (This is a measure of how well the left ventricle septum is contracting back and forth)
Mitral valve pulsed wave doppler still taken during echocardiogram. Clearly shows the four chambers of the heart and the blood flow toward and away from the transducer, red and blue colors respectively.
Brain Health
MEASUREMENT PROTOCOL
- Complex small voxel non-contrast 3D T1, T2, T2 FLAIR, mag, phase, minIP, SWI, 2/3D MRA, 2/3D MRV, 3D DTI, triple 2D DWI, ASL, CSF, SPACE, ultrasound, cognitive testing, EEG, peripheral blood markers etc.
MARKERS
- White Matter Hyperintensities: age 48
- Pineal calcification: >40 TBC
- Ventricular volume: age 48
- Cortical grey vol: age 45
- AI T1 brain age: age 44
- RAVENS PM: age 41
- Total Cerebral WMV: age 37
- WASO: age 37
NOTES
- Bi-lateral, congenital IJV
Lung Health
MEASUREMENT PROTOCOL
- Ultrasound
- Functional markers
MARKERS
- FEV1 age 22
- FVC age 26
- PEFR age 33
- A lines age 33
- DLCOc, 32.8 ml/min/mmHg, age 38.5 equivalent, a measure of the ability of the lungs air sacs, alveoli, to pass oxygen into the red blood cells in the lung capillaries
- KCOc, 4.32 1/min, age 54
- MIP & MEP are diaphragm measurements - maximum inspiratory (MIP) and expiratory (MEP) pressure scored at 155 and 117 cmH2O respectively, = to age 20 (maximum possible reduction) for both markers. These measure the strength of the double-domed diaphragm muscle below the lungs, with my Diaphragm showing no signs of weakening with chronological age.
Gastrointestinal Health
MEASUREMENT PROTOCOL
- Small bowel capsule camera (large bowel capsule camera TBC)
- Acquired 33,537 images
- Looking for lymphoma, Crohn’s ulcerations, small bowel cancer, diverticula, and polyps. Nothing found.
- Microbiome, GI Effects, other.
- Stool
MARKERS
- SCFAs & elastase: age 70+ (8/21, since have started intervention)
- Polyps negative
- Bleeds negative
- Serial FIT FOBT, Cologuard Gen 1 negative
Intestinal Tract - I swallowed this pill, the size of a baby carrot, after fasting for 24 hours. Then took laxatives for 6 hours. It reemerged 10 hours and 38 minutes later, having taken 33,537 images of my intestinal tract. Main things we were looking for: lymphoma, Crohn’s ulcerations, small bowel cancer, diverticula, and polyps. Nothing found. Most common small bowel changes with age are motility, peristalsis reduction, dysphagia and enteric neuropathy. Advantages of small bowel pillcams include screening and baseline results for n=1 study. Here are some of the pictures.
Joints
We are exploring if we can restore my joints to that of an 18 year old.
Problem
Our joints (i.e. knees, hips, etc.) break down with age. Resulting in pain, stiffness and movement restriction. While I do not have any major joint problems, I do have small aches and pains. We are testing if we can repair normal age related damage, restore vitality, and preventatively lessen future deterioration.
Therapy
Last week, I had 300 million bone marrow-derived mesenchymal stem cells (MSCs) injected into six joints over two days: both knees, shoulders, and hips as part of a clinical trial in the Bahamas. We may repeat this therapy as needed to achieve the outcome objectives.
MSC’s were manufactured by Cellcolabs. Injections were performed by Dr. Steven Sampson of Physical Longevity.
Measurement
Prior to the therapy, we completed comprehensive baseline analysis of each joint with MRI and musculoskeletal ultrasound. Here were the findings:
Joint & tendon diagnosis
+ Bilateral shoulder labral degenerative tears with paralabral cysts.
+ Tendinosis (degenerated tendons): bilateral supraspinatus rotator cuff (shoulder) with subacromial bursitis (chronic inflammation in R>L shoulders).
+ Bilateral knee chondromalacia patella (cartilage wear beneath the kneecap) with left knee mild to moderate effusion/bursitis. (fluid in knee).
+ Bilateral hip gluteus medius tendinosis (chronic degeneration). Bilateral Hip Cam impingement syndrome. (Can predispose to osteoarthritis)
What we hope we can achieve with this therapy
Improved function, mobility, and athletic performance. Elimination of aches and pains. Potential tissue regeneration and prevention of future degeneration.
Treatment plan
+ Intra Articular injection of bilateral shoulders, hips, and knees.
+ Bilateral supraspinatus rotator cuff and bursa injections.
+ Right shoulder anterior labrum injection.
Bilateral hip gluteus medius tendon injections.
What happened
The injections were completed in the Bahamas in collaboration with Cellcolabs Clinical Ltd. and Dr. Steven Sampson of Physical Longevity. Treatment was under a clinical trial approved by the national stem cell ethics committee in the Bahamas. Cellco Labs provided best-in-class, gold-standard cell manufacturing of allogeneic bone marrow-cultured mesenchymal stem cells (MSCs). 50 million MSCs were injected into each of six joints, shoulders, knees, and hips, over two days. Cells were prepared and shipped from Sweden and were cryopreserved with liquid nitrogen. Cells were checked for viability at the point of care in the Bahamas and injected under ultrasound guidance by Dr Sampson for proper deployment under strict protocol.
Hair Health
Based upon my genetics, I should be bald by now. I started greying and losing my hair in my late 20s. Been a lot of work to try and keep it.
PROTOCOL
- Custom hair formulation. Recipe:
Finasteride USP 0.25%
Minoxidil USP 5%
Azelaic Acid 1.5%
Diclofenac 0.5%
Tea Tree Oil 5%
Rosemary Oil 0.37%
Ginko Biloba 0.05%
Biotin 0.01%
Melatonin USP 0.0033%
- Grey hair reversal (BLUEPRINT discount) note: some report it working, others that it’s not. We plucked a few of my hairs and saw that melanin is being produced so it appears to be working for me.
- Topical hair formulation - I use a topical solution, 1 mL applied to my scalp each morning (before bed is ok too). I then massage my scalp with a silicon scrubber for 1-2 minutes to stimulate blood flow. The formulation I use (listed below) is based upon a genetic test I completed (Blueprint 10% off) that predicted my response to various ingredients. The company then provides you with your custom Rx formulation.
- PRP 1x 60-90 days. Recipe:
- 10x PRP concentration from 120 ccs
- .3 ml of 0.1% dutasteride
- Autologous exosomes via SuperShot
- A Cell
- Laser cap (I have the 304 laser diodes, working to find a low cost vendor)
MARKERS
- Grey+white: measuring age 41
- Quant Hamilton-Norwood: measuring age 26
Skin Health
MEASUREMENT PROTOCOL
- Multi Spectral Imaging
- Autofluorescence
- Merz
MARKERS
- Spots: Age 10
- Wrinkles: Age 10
- Texture: Age 14
- Pores: Age 50
- UV Spots: Age 62
- Brown spots: Age 11
- Red areas: Age 70
- Autofluorescence: age 32
- Multispectral imaging face age: 41
DAILY PROTOCOL
- Face wash
- Moisturizer
- Tretinoin .1%
- UVA+B mineral sunscreen
- UV environmental filters
Things we’re trialing:
- Non-bleeding microneedling with HA serum
- Cutera Excel V coolview & genesis
- Fotona Dynamis Pro 4D and other protocols
- Microbotox injections for pore shrinkage
- Sculptra
- PRF
- Renuva (autologous fat transfer)
- Whole body LED - 630 nm (red) and 830 nm (infra red) Continuous wave or pulsed up to 40 Hz Up to 200 mw/cm^2 irradiance at 6 inches 60 J/cm^2 dose at 6 inch distance.
- Be careful not to burn yourself by standing too close. Protocol (mine, is device dependent): 12 min, 3x weekly.
- Objectives:
- . accelerated healing
- . skin health
- . possible helper w/ anxiety + depression (only if applied to forehead)
- . sleep
- bought mine from http://reddotled.com
Eye Health
MEASUREMENT PROTOCOL
- Drusen volume 0
- Enhanced depth imaging optical coherence tomography subfoveal choroidal thickness high n=1 accuracy read left age 51, right age 70, prior to axial length/refractive error regression adjustment
- IOP 13 mmHg, age 38
- Accommodative distance high n=1 accuracy read TBC
- Eyelash length age 70+ (genetically short)
EYE MEASUREMENTS
- Sub-foveal choroidal thickness on enhanced depth imaging spectral domain optical coherence tomography (sfCT EDI-SD-OCT) was acquired showing 332 microns and 400 microns respectively; however, future 3D choroidal quantification methods we will perform will have lower standard deviation and higher biological age resolution
Ear Health
MEASUREMENT PROTOCOL
- Research grade digital audiometric setup with high n=1 accuracy reads
- RESULTS: Left (me), Right (my 17 yr old)
MARKERS
- Right ear normal freq: age 61
- Left ear normal freq: age 51
- Right ear EHF: age 60
- Left ear EHF: age 32
- Typmpanometric, OAE, cochlear magnetic resonance markers, waxome TBC
- Pinna age 30
Oral Health
MEASUREMENT PROTOCOL
- Plaque index, recession, attachment loss
MARKERS
- Most recent plaque index was 24.4% which is ideal
- Reduced attachment loss by 41% via specially designed procedures
DAILY PROTOCOL
- Brush 2 min (am/pm)
- Water pik (am/pm)
- Floss (am/pm)
- Tongue scraper
- Tea tree oil rinse
- CoQ10 gel
RESULTS
- My dentist reports “you have the gums of a healthy teenager”
- Improved plaque index to 63.6% (tracked plaque in mouth post brushing to assess how to improving brushing technique)
- Filled the one remaining 4 mm pocket on #11.
Gingival index and calculus index scoring 0, the lowest possible; having the same level of calculus and gum inflammation as a 17 year old.
Sleep Health
Sleep Is A Lighthouse
Perhaps the most important health/wellness practice, I’ve been working on achieving consistent, high quality sleep for years (Sleep is the new coffee). These are the things that work for me.
PROTOCOL
- Blacked out room
- Same bedtime daily
- Sleep alone
- Blue light blocking glasses
- 1 hr downtime before bed
- Temp controlled mattress
8/2023 - completed 6 months of achieving 100% sleep score performance via Whoop. Also, my one month recovery score is in the top 1.4% of all male whoop users.
Other Measurements
RED BONE MARROW
PANCREAS
MSK
PROSTATE
ARTERIES
- PBMC LIfelength QFISH median telomere length: 42
PANCREAS
- Pancreatic elastase: 70+
MSK
- Tendons enthuses US: 51
- [other]
PROSTATE
- Volume (Bolivia tribe): 59
- Volume (westerner): 30
ARTERIES
- Abdo aorta IMT: age 46
- CCA IMT: age 32
ORGANS TO COMPLETE MEASUREMENT FOR
- Thymus
- Liver & GB
- Pancreas
- Bone marrow
- Retina
- Stomach, esophagus, large Bowel/small bowel
- Mesentery
- Trachea
- Larynx
- Pharynx
- Lips
- Bronchi/oles
- Glymphatics
- Lymphatics
- Spleen
- Ureters, bladder, urethra
- Middle ear
- Nose, tongue
- Peno-scrotal
- Cartilage, ligaments
- Motor & sensory nerves, spinal cord
SEXUAL HEALTH
- Urine Chlamydia
- Urine Gonorrhea
- Hepatitis B [blood]
- HepB core antibody, surface antibody, and surface antigen
- Hepatitis C [blood]
- Herpes Simplex Virus I (Typically Oral Herpes)
- Herpes Simplex Virus II (Typically Genital Herpes)
- Oral Human Papilloma Virus (HPV)
- PCR HPV 20 subtypes
- HIV 1 [blood]
- HIV 2 [blood]
- RPR Syphilis [blood]
- Also have the Gardasil 9 HPV vaccine
BY THE NUMBERS
MEASUREMENTS
ROUTINE
- 2,250 calories daily
- ~10% Caloric Restriction
- Vegan (preference, not necessity)
- 70+lbs of veggies monthly
- 100+ pills daily
MEASUREMENTS
- biofluids, devices, imaging, fitness tests
ROUTINE
- Green Giant + 54 pills
- One hour workout
- Super Veggie
- Skin/oral/hair/eye care
- Travel to work
- Nutty Pudding
- Third dish + 34 pills
Fitness
Daily routine
Having fun workout (Oct 21)
PROTOCOL (here’s a video showing it)
- 1 hr day
- ~25 exercises
- 7 hrs wkly
- 88-105 bpm ~1 hr
- 106-159 bpm -4hr 30 min
- 159+ bpm 90 minutes
ROUTINE
- Backwards Sled, 2 min
- Posture exercises (video)
- Tricep extensions 1x25
- Face pulls 1x15
- Butterfly, 1x15
- Band pull apart (back muscles), 1x15
- Back extensions (on a hyperextension), 1x25
- Obliques (each side, on a hyperextension), 1x25
- Stretches
- Kneeling shin
- Hip flexor
- Couch
- Leg raises (for abdomen), 1x50
- Seated calf raises, 1x25
- Poliquin step ups, 3x10, each leg
- Slant board squats, 3x15
- ATG Split squats, 3x10
- Nordics, 1x10
- Reverse Nordics, 1x10
- Tibialis raises, 1x25
- IsoTib ankle rotations (each), 1x15
- Pull ups, 1x15
- Chin ups, 1x15
- 10 min HIIT (M,W,F)
- Hiking on weekends, basketball, tennis
FITNESS SCORES (ref: ACSM)
Scoring equal to top 10% of 18 year olds in the following:
- Bench press single rep max, 240lbs, top 10% of 18 year olds
- VO2 max 58.7 mL/(kg·min), top 1.5% of 18 year olds
- Leg press, single rep max. 800 lbs
- Push ups, continuous, 60
- YMCA sit and reach, 26.5 inches.
- Grip strength (dominant hand) 60 kg, above the age related peak that occurs in men at age 32.5 (Jamar Dynamometer Corporation reference data
Notable Challenges
CONGENITAL BILATERAL IJV STENOSIS
CASE NOTES DECEMBER 2021- 44yo male
- RIJV: 70-80% stenosis
- LIJV: 100% stenosis
- Below reference range flow in all positions on duplex bilateral IJV doppler
- Missing left transverse sinus on MRV; cerebral venous thrombosis?
- Severe headache symptoms causing to wake in the night, on acetazolamide 250 mg since 25th Jan 2022
- Likely cause: bilateral styloid + atlatl transverse process compression of the IJVs both sides; multiple signs of raised ICP on serial MRIs
- Possible TOS (thoracic outlet syndrome seen on subclavian MRA)
- 20 years history of nocturnal bruxism untreated until 2021
- No previous stroke, TIA, aphasia, blurred vision or other medical conditions.
- Deciding next steps RE tests and surgical intervention.
LUNG B LINES
- 9 when I should have 2
- Possible pathological confirmation via hyperpolarized MRI
- Possible elimination via multi-component nebulised protocol
GRAY HAIR
- Excessive stress, chronic depression from age 20-40 whitened my hair
- Struggling to reverse it (8/23 update 8/23 - we’ve made some meaningful progress with this formulation “Blueprint for 7% off”)
HEART REJUVENATION
- Several heart markers including LV septal A’ mitral, Aortic root diameter, LA E’ latbasal and RVSP are all coming in decades older than my chrono age. No symptoms.
- Need to formulate a plan
MAX HR
- In twelve months, improved from 169 bpm to 183 bpm
- Struggling to make further gains
This work is licensed under a Attribution-NonCommercial 4.0 International | Consult your doctor for what’s right for you.
Medical disclaimer
This website, including any experimental results presented, is for informational purposes only and does not constitute medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease. Individuals seeking medical advice should consult with a licensed physician.
Biological age measurements and claims
Any claims regarding the measurement or reversal of biological age are preliminary and can be influenced by various biostatistical errors, including statistical variation, reference range relevancy, and clinical outcome significance. Ongoing, formal peer-reviewed studies are essential for validating these biological age tests for FDA approval (or its international equivalent) and confirming any clinically relevant changes in biological age. The data presented reflect our team's rigorous efforts to adhere to current scientific and biostatistical standards, while formal peer-reviewed validation studies are underway. Please note: These tests are experimental and intended solely for research purposes. They should not replace or supplement any clinical tests recommended by licensed medical professionals."
Context
The protocol presented on this website is based on scientific research, ranging from mouse studies to meta-analyses of randomized controlled trials and international clinical practice guidelines. These have been carefully reviewed for their unique relevance to my personal situation. The protocol encompasses a mix of on-label, off-label, and unlicensed therapies, as well as research-use-only tests. Some of these tests and therapies are still under scientific investigation and have not yet received on-label licensing for specific health conditions. All tests and therapies, regardless of their licensing status, carry risks. These risks have been assessed for my personal use by a specialized team of clinicians and scientists. This protocol represents an experimental clinical research project. Results will be periodically published in peer-reviewed journals, adhering to international quality standards relevant to various types of clinical studies, including case reports, randomised controlled trials, and systematic reviews. Case reports, case series, and systematic reviews are important components of evidence-based medicine, helping inform the design of gold-standard randomised controlled trials and guiding clinical practice.
Rx
The use of Prescription only Medicines (PoMs) such as HGH, acarbose, rapamycin, metformin, thyroxine, testosterone, statins, phenylbutyric acid, tadalafil and others discussed in this protocol should not be considered an endorsement or promotion of these products. PoMs should only be prescribed by a licensed doctor who has assessed that the benefits and risks are acceptable for the individual and acquired through licensed pharmacies in a jurisdictionally legal manner. The prescribing doctor should be made aware of all other PoMs being taken and other relevant interventions such as foods, supplements and medical history to enable accurate assessment for safe prescribing and monitoring of combination interventions.
This web site is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.
Medical disclaimer
This website, including any experimental results presented, is for informational purposes only and does not constitute medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease. Individuals seeking medical advice should consult with a licensed physician.
Biological age measurements and claims
Any claims regarding the measurement or reversal of biological age are preliminary and can be influenced by various biostatistical errors, including statistical variation, reference range relevancy, and clinical outcome significance. Ongoing, formal peer-reviewed studies are essential for validating these biological age tests for FDA approval (or its international equivalent) and confirming any clinically relevant changes in biological age. The data presented reflect our team's rigorous efforts to adhere to current scientific and biostatistical standards, while formal peer-reviewed validation studies are underway. Please note: These tests are experimental and intended solely for research purposes. They should not replace or supplement any clinical tests recommended by licensed medical professionals."
Context
The protocol presented on this website is based on scientific research, ranging from mouse studies to meta-analyses of randomized controlled trials and international clinical practice guidelines. These have been carefully reviewed for their unique relevance to my personal situation. The protocol encompasses a mix of on-label, off-label, and unlicensed therapies, as well as research-use-only tests. Some of these tests and therapies are still under scientific investigation and have not yet received on-label licensing for specific health conditions. All tests and therapies, regardless of their licensing status, carry risks. These risks have been assessed for my personal use by a specialized team of clinicians and scientists. This protocol represents an experimental clinical research project. Results will be periodically published in peer-reviewed journals, adhering to international quality standards relevant to various types of clinical studies, including case reports, randomised controlled trials, and systematic reviews. Case reports, case series, and systematic reviews are important components of evidence-based medicine, helping inform the design of gold-standard randomised controlled trials and guiding clinical practice.
Rx
The use of Prescription only Medicines (PoMs) such as HGH, acarbose, rapamycin, metformin, thyroxine, testosterone, statins, phenylbutyric acid, tadalafil and others discussed in this protocol should not be considered an endorsement or promotion of these products. PoMs should only be prescribed by a licensed doctor who has assessed that the benefits and risks are acceptable for the individual and acquired through licensed pharmacies in a jurisdictionally legal manner. The prescribing doctor should be made aware of all other PoMs being taken and other relevant interventions such as foods, supplements and medical history to enable accurate assessment for safe prescribing and monitoring of combination interventions.
This web site is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.